Glycogen Storage Disease

Jubiz and Rallison, Archives of Internal Medicine (1974), 1193 report on four patients with glycogen storage disease, two with debranching enzyme system deficiency, one with phosphorylase deficiency and one with glucose-6-phosphatase deficiency. These patients were treated with PHT for more than two years and there was a good response. This was evidenced by a reduction in liver size and hepatic glycogen content. Hyperlacticacidemia improved.

1193. Jubiz, W. and Rallison, M. L., Diphenylhydantoin treatment of glycogen storage diseases, Arch. Intern. Med., 134: 418-421, 1974.